84-4437-67　SPD (Surfactant Associated Protein D, SFTPD, COLEC7,PSP-D, SFTP4, SP-D, Pulmonary Surfactant Protein D,Collectin-7, Lung surfactant protein D) 200ul　365152

特徴

• Surfactant protein D (SP-D) belongs to the collectin family.
• These proteins are oligomeric proteins composed of carbohydrate-recognition domains(CRD)attached to collagenous regions.
• Collectins are structurally similar to the ficolins although they make use of different CRD structures: C-type lectin domain for the collectins.
• The lung is the major site of synthesis of SP-D, where the molecules are produced and secreted onto the epithelial surface by alveolar type Ⅱcells and unciliated bronchial epithelial cells.
• SP-D is also found in different epithelial cells of the gastrointestinal tract and in epithelial cells of various exocrine glands.
• SP-D is an important factor in the pulmonary anti-microbial defense.
• The anti-microbial defense mechanisms of SP-D are direct opsonization, neutralization and agglutination.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 0.5-3ug/mlImmunohistochemistry (Paraffin): 5-30ug/ml Immunocytochemistry: 5-30ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.