84-4437-65　SPC (Surfactant Associated Protein C, SFTPC, PSP-C, SFTP2, SP-C, SP5, Pulmonary Surfactant Protein C, Pulmonary surfactant-associated proteolipid SPL Val) 200ul　365150

特徴

• SP-C is a fragment of a much larger precursor protein of 21kD.
• The precursor contains an exceedingly hydrophobic region of 34aa that comprises most of the mature SP C, and a unique poly-valine domain.Pulmonary surfactant-associated protein C is a membrane protein which manufactures surfactant.
• Humans and animals born lacking SP-C tend to develop progressive interstitial pneumonitis.
• The SFTPC gene encodes pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth.
• It is produced exclusively by type II alveolar epithelial cells in the lung.
• Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 0.5-2ug/mlImmunohistochemistry (paraffin): 5-20ug/ml Immunocytochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher.
• Positive Control Included:365150A: SPC, Positive ControlSupplied as a recombinant protein SPC in loading buffer (100mM Tris, pH 6.8, 1% SDS, 150mM sodium chloride, 50mM DTT, 0.02% BPB, 0.02% sodium azide, 50% glycerol)
• DAB: 10ul/wellECL: 5ul/wellStore at -20°C.
• Stable for 6 months after receipt.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.