84-4437-08　［受注停止］Smad6 (Mothers Against Decapentaplegic Homolog 6, MADH6, MADH7) 200ul　365093

特徴

• SMAD family member 6, also known as SMAD6 is a protein that, as its name describes, is a homolog of the Drosophila gene "mothers against decapentaplegic".
• It belongs to the SMAD family of proteins, which belong to the TGFbeta superfamily of modulators.
• Like many other TGFbeta family members SMAD6 is involved in cell signalling.
• It acts as a regulator of TGFbeta family (such as bone morphogenetic proteins) activity by competing with SMAD4 and preventing the transcription of SMAD4's gene products.
• There are two known isoforms of this protein.
• The SMAD proteins are homologs of both the drosophila protein, mothers against decapentaplegic (MAD) and the C.
• elegans protein SMA.
• The name is a combination of the two.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- CNPYHFSRLC GPESPPPPYS RLSPRDEYKP LDLSDSTLSY TETEATNSLI TAPGEFSDAS MSPDATKPSH WCSVAYWEHR TRVGRLYAVY DQAVSIFYDL PQGSGFCLGQ LNLEQRSESV RRTRSKIGFG ILLSKEPDGV WAYNRGEHPI FVNSPTLDAP GGRALVVRKV PPGYSIKVFD FERSGLQHAP EPDAADGPYD PNSVRISFAK GWGPCYSRQF ITSCPCWLEI LLNNP
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.