84-4436-17　SDC1 (Syndecan 1, CD138, SDC, SYND1, Syndecan Proteoglycan 1) 200ul　365003

特徴

• Syndecan 1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family.
• The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein.
• The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.
• Altered syndecan-1 expression has been detected in several different tumor types.
• While several transcript variants may exist for this gene, the full-length natures of only two have been described to date.
• These two represent the major variants of this gene and encode the same protein.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- SGAG ALPDITSSHT PSTWKDLGPV TTTATAPEPT SPDAIAASTT ILPTGEQPEG GRAVLLAEVE PGLTAQKEAT HPPSETTLHP TTHSVSTARA TMAPGPATSH PHRDVQPDHH ETSAPTGRGR MEPHRPHVEE GGPPATEKAA EEDPSTQIPV GEGSGEQDFT FDLSGENAAG AAGEPGSRNG APEDPEATGA TGASQGLLDR KEVLGGVIAG GLVGLIFAVC LVGFMLYRMK KKDEGSYSLE EPKQANGGAY QKPTK
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.