84-4436-05 SCGB3A1 (Secretoglobin Family 3A, Member 1, HIN1, HIN-1, LU105, PnSP-2, UGRP2, Cytokine High In Normal-1, Pneumo Secretory Protein 2, High in normal 1, Uteroglobin-related protein 2) 200ul 364991
84-4436-05 SCGB3A1 (Secretoglobin Family 3A, Member 1, HIN1, HIN-1, LU105, PnSP-2, UGRP2, Cytokine High In Normal-1, Pneumo Secretory Protein 2, High in normal 1, Uteroglobin-related protein 2) 200ul 364991
Breast cancer progresses from atypical hyperproliferation to in situ and then invasive carcinomas before culminating in metastatic disease.
Ductal carcinoma in situ (DCIS) is thought to be the precursor of invasive ductal carcinoma.
The deduced 104aa HIN1 protein contains a signal peptide and is conserved in several species.
HIN1 was highly expressed in breast tissue from a woman in the twenty-fifth week of pregnancy.
In situ hybridization analysis confirmed the expression of HIN1 in small ducts and lobules, irrespective of their proliferation and hormone receptor status.
HIN1 was also highly expressed in other tissues with branching ductal epithelia.
No expression was detected in large or DCIS ducts.
Western blot analysis showed expression of an 8kD protein.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.5-2ug/ml Immunocytochemistry: 5-20ug/mlImmunohistochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol
Specificity:Recognizes human SCGB3A1. Species Crossreactivity: porcine
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu Po
Immunogen:Recombinant protein corresponding to Phe21-Gly104 of human SCGB3A1, expressed in E. coli