84-4435-91　SBEM (Small Breast Epithelial Mucin, MUCL1, Mucin-Like Protein 1, Protein BS106, Mucin-like protein 1) discontinued 200ul　364977

特徴

• Small breast epithelial mucin (SBEM) is a recently described gene product that shows promise as a new breast biomarker.Using expression profiling of EST and SAGE databases, Miksicek et al.
• (2002) identified SBEM, which encodes a putative 90aa protein.
• SBEM has a hydrophobic signal peptide, suggesting that it is a secreted protein subject to proteolytic processing, and it is predicted to be O-glycosylated.
• SBEM contains 3 tandem copies of a neutral octapeptide core repeat, and its N- and C-terminal regions are charged and fairly polar.
• These features are similar to many sialomucins, although the protein lacks a transmembrane domain and is shorter than most other known epithelial mucins.
• RNA hybridization analysis showed SBEM expression in only adult mammary and salivary glands.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
• AA Sequence:MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-NPTTAAPADT YPATGPADDE APDAETTAAA TTATTAAPTT ATTAASTTAR KDIPVLPKWV GDLPNGRVCP
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.