84-4435-66　S100A11 (S100 Calcium Binding Protein A11, S100-A11, S100C, MLN70, Protein S100-C, Calgizzarin, Metastatic lymph node gene 70 protein, Protein S100-A11, N-terminally processed) 200ul　364952

特徴

• Is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs.
• S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation.
• S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.
• S100C may function in motility, invasion, and tubulin polymerization.
• Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
• By in situ hybridization, Moog-Lutz et al.
• mapped the calgizzarin, or S100C, gene to 1q21.
• By analysis of clones from this region, Wicki et al.
• determined that S100A11 is part of the S100 gene cluster and is located near S100A10
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
• AA Sequence:MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGS-MSKVSPTETE RCIESLLAVF QRYAGREGDN LKLSKKEFRT FMNTELASFT KNQKDPAVVD RMMKRLDINS DGQLDFQEFL NLIGGIAVAC HDALLVQPPH P
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.