84-4434-93　［受注停止］REG1b (Regenerating Islet Derived Protein 1 Beta, PSPS2, REGH, REGI-BETA, REGL, Pancreatic Stone Protein, Pancreatic Thread Protein, Lithostathine 1 Beta, Secretory Pancreatic Stone Protein 2) 200ul　364880

特徴

• Lithostathine-1-beta is a type I subclass member of the Reg gene family.
• The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins.
• This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein.
• The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis.
• Reg family members REG1A, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
• The proteins encoded by REG1A and REG1B comprised 166aa and differed by only 22aa.
• The expression of REG1B was observed in pancreas and liver.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEFELRR Q- QESQTELP NPRISCPEGT NAYRSYCYYF NEDPETWVDA DLYCQNMNSG NLVSVLTQAE GAFVASLIKE SSTDDSNVWI GLHDPKKNRR WHWSSGSLVS YKSWDTGSPS SANAGYCASL TSCSGFKKWK DESCEKKFSF VCKFKN
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.