84-4434-44　［受注停止］PURA (Purine Rich Element Binding Protein A, PUR-A, PUR1, PUR-ALPHA, PURALPHA, Transcriptional activator protein Pur-alpha, Purine-rich single-stranded DNA-binding protein alpha) 200ul　364831

特徴

• Transcriptional activator protein Pur-alpha is a sequence-specific, single-stranded DNA-binding protein.
• It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans.
• Thus, it is implicated in the control of both DNA replication and transcription.
• Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia
• This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene.
• May play a role in the initiation of DNA replication and in recombination.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.