Receptor-type tyrosine-protein phosphatase O is a receptor-type protein tyrosine phosphatase containing a single intracellular catalytic domain with a characteristic signature motif
The gene product, which has a transmembrane domain, is an integral membrane protein.
Several alternatively spliced transcript variants, some of which encode different isoforms of the protein, have been described.
These variants exhibit tissue-specific expression
The human GLEPP1 gene predicts a protein of 1188aa.
The 1159aa predicted mature protein contains a large extracellular domain, a single transmembrane domain, and a single intracellular PTPase domain.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes mouse PTPRO.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Mo
Immunogen:Recombinant protein corresponding to Phe948-Met1205of mouse PTPRO, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.