84-4433-81　PSGL1 (P-Selectin Glycoprotein Ligand 1, CD162, SELPLG, CLA, Selectin P Ligand) 200ul　364769

特徴

• SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes.
• As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin.
• The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.
• P-selectin glycoprotein ligand-1 is a glycoprotein found on white blood cells and endothelial cells that binds to P-selectin (P stands for platelet).
• It is one of a family of selectins that includes E-selectin (endothelial) and L-selectin (leukocyte).
• PSGL-1 can bind to all three members of the family but binds best (with the highest affinity) to P-selectin.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGS-SERATEK IATTDPTAPG TGGTAVGMLS TDSATQWSLT SVETVQPAST EVETSQPAPM EAETSQPAPM EAETSQPAPM EAETSQPAPM EADTSQPAPM EAETSQPAPN EAETSKPAPT EAETSKPAPT EAETTQLPRI QAVKTLFTTS AATEVPSTEP TTMETASTES NESTIFLGPS VTHLPDSGLK KGLIVTPGNS PAPTLPGSSD LIPVKQCLLI ILILASLATI FLVCTVVLAV RLSRKTHMYP VRNYS
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.