Protein Z is a member of the coagulation cascade, the group of blood proteins that leads to the formation of blood clots.
It is vitamin K-dependent, and its functionality is therefore impaired in warfarin therapy.
It is a glycoprotein.
Structural analysis of protein Z will allow better understanding of its function.
From a Ramachandran plot, the secondary structure of Protein Z was determined.
The Ramachandran plot utilizes mathematical equations to determine the possible angles of the amino acids within the primary sequence of Protein Z.
The possible angles results in a plot of possible secondary structures.
The Ramachandran plot for protein Z indicates it will form alpha helices.
The final structure, all aphla domain, was determined by x-ray diffraction.
It consists of chain A and B, which are both helix-loop-helix motifs.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse PROZ.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Ser23-Lys399 of mouse PROZ, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.
