84-4433-08　［受注停止］PLVAP (Plasmalemma Vesicle Associated Protein, FELS, PV-1, PV1, gp68, Fenestrated-Endothelial Linked Structure Protein, Plasmalemma vesicle protein 1) 200ul　364696

特徴

• PLVAP is a type II integral membrane protein with a short N-terminal cytoplasmic tail, a single-span transmembrane domain, and a large C-terminal extracellular domain consisting mostly of alpha helices.
• It also contains 2 coiled-coil domains predicted to contribute to dimer formation.
• The extracellular domain has 4 N-glycosylation sites, a proline-rich region, and regular spacing of cysteine residues.
• The deduced 439aa mouse Plvap protein contains a consensus casein kinase II phosphorylation site that is not found in the human protein.
• Rat Plvap contains 2 casein kinase II phosphorylation sites.
• Northern blot analysis revealed a single PLVAP transcript of about 2.4 kb in pancreas, kidney, placenta, muscle, lung, heart, and liver.
• No signal was detected in brain or testis.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RVIYTNNQ RYMAAIILSE KQCRDQFKDM NKSCDALLFM LNQKVKTLEV EIAKEKTICT KDKESVLLNK RVAEEQLVEC VKTRELQHQE RQLAKEQLQK VQALCLPLDK DKFEMDLRNL WRDSIIPRSL DNLGYNLYHP LGSELASIRR ACDHMPSLMS SKVEELARSL RADIERVARE NSDLQRQKLE AQQGLRASQE AKQKVEKEAQ AREAKLQAEC SRQTQLALEE KAVLRKERDN LAKELEEKKR EAEQLRMELA IRNSALDTCI KTK
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.