84-4432-80　PL (Placental Lactogen, CSH1, hCS-A, CSA, CSMT, Chorionic Somatomammotropin Hormone 1, Choriomammotropin) 200ul　364669

特徴

• Human placental lactogen (HPL), also called human chorionic somatomammotropin, is a polypeptide placental hormone.
• Its structure and function is similar to that of human growth hormone.
• It modifies the metabolic state of the mother during pregnancy to facilitate the energy supply of the fetus.
• HPL is an anti-insulin.
• HPL consists of 190aa that are linked by two disulfite bonds and is secreted by the syncytiotrophoblast during pregnancy.
• Its molecular weight is 22,125.
• Like human growth hormone HPL is encoded by genes on chromosome 17q22-24.
• Its biologic half-life is 15 minutes.
• HPL is only present during pregnancy with maternal serum levels rising in relation to the growth of the fetus and placenta.
• Maximum levels are reached near term, typically to 5-7mg/ml.
• Higher levels are noted in patients with multiple gestation.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QTV PLSRLFDHAM LQAHRAHQLA IDTYQEFEET YIPKDQKYSF LHDSQTSFCF SDSIPTPSNM EETQQKSNLE LLRISLLLIE SWLEPVRFLR SMFANNLVYD TSDSDDYHLL KDLEEGIQTL MGRLEDGSRR TGQILKQTYS KFDTNSHNHD ALLKNYGLLY CF
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.