84-4432-53　［受注停止］PIK3Cd (Phosphoinositide-3-Kinase Catalytic Delta Polypeptide, p110D, P110delta, Phosphoinositide-3-Kinase C, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110kD catalytic subunit delta) 200ul　364642

特徴

• Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids.
• The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha, p110-beta, and p110-gamma.
• p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins and with GTP-bound Ras
• Like p110-alpha and p110-beta, p110-delta binds p85 adaptor proteins and GTP-bound Ras.
• These 3 class I PI3Ks were indistinguishable at the level of p85 adaptor protein selection or recruitment to activated receptor complexes.
• However, unlike p110-alpha, p110-delta does not phosphorylate p85, but instead has an autophosphorylation activity.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.