Polymeric immunoglobulin receptor is a Fc receptor which facilitates the secretion of IgA and IgM.
The poly-Ig receptor is expressed on several glandular epithelia including those of liver and breast.
It mediates transcellular transport of polymeric immunoglobulin molecules
It is a member of the immunoglobulin superfamily (Hood et al., 1985).
The receptor has 5 units with homology to the variable (V) units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
AA Sequence:MGHHHHHHSGSEF-K NNADLQVLEP EPELLYKDLR SSVTFECDLG REVANDAKYL CRKNKETCDV IINTLGKRDP AFEGRILLTP RDDNGRFSVL ITGLRKEDAG HYQCGAHSSG L
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes rat PIGR.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to Lys230-Leu331 of rat PIGR, fused to N-terminal His-Tag expressed in E. coli.
