PI16 may serve as a marker following prostatectomy for prostate cancer.
This protein binds with high affinity to PSP94
PI16 expression is enhanced after serum stimulation of primary cardiomyocytes and is rapidly secreted into the conditioned medium of cardiomyocytes.
PI16 is overexpressed in the hypertrophic and failing heart and inhibits cardiomyocyte growth.
Suppression of endogenous PI16 expression in primary cardiomyocytes significantly enhances cardiomyocyte size.
Transgenic mice overexpressing PI16 in a cardiomyocyte-specific manner show normal cardiac function but have smaller hearts with hypotrophic cardiomyocytes.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlImmunohistochemistry: 5-20ug/mlImmunocytochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：bovine
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes bovine PI16.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Bo
Immunogen：Recombinant protein corresponding to Leu28-Pro442 of bovine PI16 expressed in E. coli.
