84-4432-23　PF4V1 (Platelet Factor 4 Variant 1, CXCL4L1, PF4var1, CXCL4V1, SCYB4V1, SCYB4-V1, CXCL4-V1, Chemokine(C-X-C-Motif)Ligand 4 Variant) 200ul　364612

特徴

• The PF4V1 gene comprised 3 exons and 2 introns.
• Exon 1 coded for a 34aa hydrophobic leader sequence that had 70% sequence homology with the leader sequence of PF4.
• Exon 2 coded for a 42aa segment that was 100% identical with the corresponding segment of the mature PF4 sequence.
• Exon 3 coded for the 28-residue carboxy-terminal region corresponding to a domain specifying heparin-binding and cellular chemotaxis.
• Human Gene Mapping Workshop 10.5 assigned the PF4V1 gene to 4q12-q21, the same region as that which carries the PF4, IP10, and MGSA genes.
• Green et al.
• (1989) suggested that the polymorphism detected in the PF4 gene by Guzzo et al.
• (1987) was in fact a polymorphism of the PF4V1 gene.Poncz et al.
• (1991) demonstrated that the PF4V1 and beta-thromboglobulin genes are located in a region of less than 190 kb.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-MSSAARSRLT RATRQEMLFL ALLLLPVVVA FARAEAEEDG DLQCLCVKTT SQVRPRHITS LEVIKAGPHC PTAQLIATLK NGRKICLDLQ ALLYKKIIKE HLES
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.