84-4430-95　OIT3 (Oncoprotein Induced Transcript 3, LZP, Liver-specific zona pellucida domain-containing protein) 200ul　364486

特徴

• OIT3 contains one EGF-like domain and one ZP domain.
• It may be involved in hepatocellular function and development.
• OIT3 is liver-specific and is expressed only in the hepatocytes; down-regulated in hepatocellular carcinoma (HCC) and HCC cell lines.
• LZP contains an N-terminal signal peptide, followed by 3 epidermal growth factor (EGF)-like domains and a zona pellucida (ZP) domain in its C-terminal region.
• LZP also contains several N-glycosylation sites
• The 546aa mouse Lzp protein shares 89% identity with human LZP.
• Northern blot analysis of several human tissues detected a 2.4-kb transcript only in liver.
• Northern blot analysis of whole mouse embryos detected 2 Lzp variants that differed in the length of the UTR and the poly(A) signal used.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RGLVLSEDNH TCQVPVLCKS SAIEVSVPRE LVGGLELFLT NTSCRGVSNG THVNIIFSLK TCGTVVDVVN DKIVASNLVT GLPKQTPGSS GDIIIRTSKL LIPVTCEFPR LYTISEGYVP NLRNAPLEIR SRNHGIFPFT LEIFKDHEFE EPYRETLPTL KLRDSLYFGI EPLVHVSGLE SLVESCFATP TAKVDEILKY YLIRDGCVSD DSVKQYSSRD HLAKHFQVPV FKFVGKDHKE VFLHCRVLVC GVLDERSRCA QGCHRRVRRE AGED
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.