84-4430-22　NPTX2 (Neuronal Pentraxin II, NARP2, NP-II, NP2, Apexin) 200ul　364413

特徴

• Neuronal pentraxin 2 been identified by Hsu and Perin.
• It is related to a secreted member of the pentraxin family identified first in rats, termed NPTX1.
• Unlike NPTX1, which is expressed almost exclusively in neuronal tissues, NPTX2 is expressed in brain, testis, pancreas, liver, heart, and skeletal muscle.
• The protein is also being referred to as NARP, a secreted protein with features of a calcium dependent lectin, which acts as a neurotrophic factor promoting neuronal migration and dendritic outgrowth of neurons with the same potency as neurotrophins and growth factors.
• Reti et al have localized NARP in vasopressin neurons of the hypothalamus and in the posterior pituitary.
• Several stimuli known to trigger vasopressin release, i.,e., hypovolemia, dehydration, and endotoxin, elevate plasma Narp levels.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- DTMGDLPRDP GHVVEQLSRS LQTLKDRLES LEHQLRANVS NAGLPGDFRE VLQQRLGELE RQLLRKVAEL EDEKSLLHNE TSAHRQKTES TLNALLQRVT ELERGNSAFK SPDAFKVSLP LRTNYLYGKI KKTLPELYAF TICLWLRSSA SPGIGTPFSY AVPGQANEIV LIEWGNNPIE LLINDKVAQL PLFVSDGKWH HICVTWTTRD GMWEAFQDGE KLGTGENLAP WHPIKPGGVL ILGQEQDTVG GRFDATQ
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.