84-4430-08 NOV (Nephroblastoma Overexpressed Gene, CCN3, IGFBP9, NOVH, IBP-9, Insulin-like growth factor-binding protein 9, Protein NOV homolog) 200ul 364399
84-4430-08 NOV (Nephroblastoma Overexpressed Gene, CCN3, IGFBP9, NOVH, IBP-9, Insulin-like growth factor-binding protein 9, Protein NOV homolog) 200ul 364399
NOV is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins.
CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.It is a member of the CCN family of proteins that includes connective tissue growth factor.
The proteins share several common structural motifs: a consensus sequence present in IGF (insulin-like growth factor)-binding proteins (the IGFBP motif), an oligomeric complex-forming domain first identified in von Willebrand factor (VWF), a binding domain to soluble and matrix molecules, and a dimerization (CT) domain.
All CCN family members are thought to be involved in the control of cell proliferation.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes rat NOV.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Rt
Immunogen:Recombinant protein corresponding to Ala156-Met351 of rat NOV, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.