ZNF384 contains long CAG trinucleotide repeats coding consecutive glutamine residues.
The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity.
Nuclear Matrix Protein 4appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1.
Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling.
Multiple transcript variants encoding several isoforms have been found for this gene.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.