NDRG2 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily.
The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth.
This gene may be involved in glioblastoma carcinogenesis.
Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined
Kalaydjieva et al.
(2000) identified the homologous human genes, which they referred as NDRG2 and NDRG3.
Kalaydjieva et al.
(2000) stated that the 3 known human NDRG proteins show considerable homology: 54% amino acid sequence identity between NDRG1 and NDRG2, 67% between NDRG1 and NDRG3, and 58% between NDRG2 and NDRG3.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes rat NDRG2.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to Ala2-Pro300 of rat NDRG2, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E .coli.
