84-4429-24　［受注停止］NCK1 (Non Catalytic Region Of Tyrosine Kinase Adaptor Protein 1, NCKalpha, NCKa, NCK adaptor protein 1, Cytoplasmic protein NCK1, SH2/SH3 adaptor protein NCK-alpha) 200ul　364316

特徴

• The Cytoplasmic protein NCK1 Protein belongs to the adaptor family of proteins.
• The Nck family has two known members in human cells.(Nck-1/Nckalpha and NcK2/NcKbeta), two in mouse cells(mNckalpha and mNckbeta/Grb4) and one in drosophila( Dock means dreadlocks-ortholog).
• The two murine gene products exhibits 68% aminoacid identity to one another,with most of the sequence variation being located to the linker regions between the SH3 and SH2 domains, and are 96% identical to their human counterparts.
• While human nck-1 gene has been localised to the 3q21 locus of chromosome 3,the nck-2 genecan be found on chromosome 2 at the 2q12 locus.
• The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.