Metaxin 1, is a protein located on the outer membrane of mitochondria, is a component of the mitochondrial protein translocation apparatus.that spans the 6-kb interval separating the glucocerebrosidase gene (GBA) from the thrombospondin III geneon chromosome 3.
Metaxin (so named from a Greek word for 'in between') and GBA are transcribed convergently; their major polyadenylation sites are only 431 bp apart.
On the other hand, metaxin and the Tsp3 gene are transcribed divergently and share a common promoter sequence.
The cDNA from metaxin encodes a 317aa protein which lacks both a signal sequence and a consensus sequence for N-linked glycosylation.
Metaxin protein is expressed ubiquitously in tissues of the young adult mouse.
No close homologs were found in the DNA or protein databases.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human MTX1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Val175-Leu387 of human MTX1, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
