Malonyl-CoA decarboxylase (EC 4.1.1.9) catalyzes the conversion of malonyl-CoA to acetyl-CoA and carbon dioxide.
It is thought to be involved in aspects of fatty acid biosynthesis and oxidation (Sacksteder et al., 1999).
Malonyl-CoA decarboxylase is found most often in the liver, brain, heart, and skeletal muscle (Sacksteder et al., 1999).
Gao et al.
(1999) searched expressed sequence tag databases to identify human cDNAs with homology to the goose malonyl-CoA decarboxylase cDNA sequence.
The 1,479-nucleotide human cDNA sequence is 70% identical to that of goose.
FitzPatrick et al.
(1999) identified a 2.1-kb human MCD cDNA encoding a 454aa protein that shows 70.3% aa identity to goose Mcd.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.5-2ug/mlImmunohistochemistry (paraffin): 5-20ug/ml Immunocytochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human MLYCD. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to Ser191-Leu493 of human MLYCD, expressed in E. coli.
