84-4427-32　MFN1 (Mitofusin 1,Hfzo1, Hfzo2, Transmembrane GTPase MFN1, Fzo homolog) 200ul　364126

特徴

• Mitofusin-1 is a mediator of mitochondrial fusion.
• This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo).
• They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
• The deduced 741aa protein contains an N-terminal GTPase domain and a transmembrane domain near the C terminus.
• MFN1 shares 60% identity with MFN2, with the most extensive homology in the GTPase domains.
• The N- and C-terminal ends are more variable.
• When stably expressed in COS-7 cells, MFN1 colocalized with mitochondrial markers.
• Overexpression of MFN1 caused perinuclear mitochondrial clustering.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.