84-4427-17　MEPE (Matrix Extracellular Phosphoglycoprotein, OF45, Asarm Motif-Containing, Osteoblast/Osteocyte Factor 45) 200ul　364111

特徴

• The predicted 525aa MEPE protein has a signal peptide, 2 N-glycosylation motifs, a glycosaminoglycan-attachment site, an RGD cell-attachment motif, and phosphorylation motifs.
• Rowe et al.
• (2000) noted that MEPE shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including dentin sialophosphoprotein (DSPP ), osteopontin (SPP1 ), and dentin matrix protein-1 (DMP1 ).
• RT-PCR detected MEPE expression in bone marrow and brain.
• High-level expression of a 2-kb MEPE transcript was detected in 4 OHO tumor samples.
• Rowe et al.
• (2000) concluded that MEPE is a candidate gene for an OHO tumor-secreted phosphaturic factor that may play a role in the pathophysiology of tumor-induced osteomalacia.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- STHRIQHNI DYLKHLSKVK KIPSDFEGSG YTDLQERGDN DISPFSGDGQ PFKDIPGKGE ATGPDLEGKD IQTGFAGPSE AESTHLDTKK PGYNEIPERE ENGGNTIGTR DETAKEADAV DVSLVEGSND IMGSTNFKEL PGREGNRVDA GSQNAHQGKV EFHYPPAPSK EKRKEGSSDA AESTNYNEIP KNGKGSTRKG VDHSNRNQAT LNEKQRFPSK GKSQGLPIPS RGLDN
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.