84-4427-03　MDC (Macrophage Derived Chemokine, CCL22, ABCD1, DC/B-CK, SCYA22, STCP1, Chemokine C-C-Motif Ligand 22, Small Inducible Cytokine Subfamily A(Cys-Cys)Member 22, Stimulated T-Cell Chemotactic Protein 1) 200ul　364097

特徴

• CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16.
• Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes.
• The CC cytokines are proteins characterized by two adjacent cysteines.
• The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes.
• It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes
• The product of this gene binds to chemokine receptor CCR4.
• This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-MASLKTPLLA ALVFLVLTLQ ATEAGPYGAN VEDSICCRDY IRHPLPLRLL KYFYWTSDSC RRPGVVFLTV KDREICADPR VPWVKKLLQK LDP
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap