Microtubule-associated protein 6 is a microtubule-associated protein.
calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization.
Two transcript variants encoding distinct isoforms have been identified for this gene.Mammalian cells often contain abundant subpopulations of microtubules that are stable to both drug- and cold temperature-induced disassembly.
Such microtubules are apparently universal in the neurite extensions of neuronal cells
The protein, called stable tubule-only polypeptide (STOP) by them, is a 100.5kD polypeptide.
The central region of the predicted 952aa polypeptide contains 5 tandem repeats of 46aa.
STOP also contains a putative SH3-binding motif near its N terminal.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse MAP6.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：E. coli-expressed recombinant protein corresponding to Gln177 thru Glu387 of mouse MAP6 (UniProt accession #Q7TSJ2) with an N-terminal His tag
