84-4426-56　MAP4 (Microtubule Associated Protein 4) 200ul　364050

特徴

• Microtubule-associated protein 4 is a major non-neuronal microtubule-associated protein.
• This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU).
• This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion.
• Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules
• The phosphorylation of this protein affects microtubule properties and cell cycle progression.
• Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed, the full-length nature of three of which are supported.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- TSTKPSSSA PRVSRLATTV SAPDLKSVRS KVGSTENIKH QPGGGRAKVE KKTEAATTAG KPEPNAVTKA AGSIASAQKP PAGKVQIVSK KVSYSHIQSK CGSKDNIKHV PGGGNVQIQN KKVDISKVSS KCGSKANIKH KPGGGDVKIE SQKLNFKEKA QAKVGSLDNV GHLPAGGAVK TE
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.