84-4426-45　MAOA (Monoamine Oxidase A, MAO-A, Amine oxidase [flavin-containing] A) 200ul　364039

特徴

• Monoamine oxidase A is an isozyme of monoamine oxidase.
• It preferentially deaminates norepinephrine (noradrenaline), epinephrine (adrenaline), serotonin, and dopamine (dopamine is equally deaminated by MAO-A and MAO-B).
• It is inhibited by clorgiline and befloxatone.
• This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin.
• The protein localizes to the outer mitochondrial membrane.
• The gene is adjacent to a related gene (MAOB) on the opposite strand of chromosome X.
• Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome.
• MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34 percent in patients with major depressive disorder.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.