Lysophospholipids (LysoPLs) are detergent-like intermediates in phospholipid metabolism.
Increased LysoPL levels have been detected in a variety of diseases including atherosclerosis and hyperlipidemia.
In some cases, increased levels of LysoPLs are hypothesized to result from a dysfunction of LysoPL-regulating enzymes including lysophospholipases, which act on biologic membranes to regulate the level of LysoPLs by hydrolysis
Acyl-protein thioesterase 1 hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms.
The use of alternate polyadenylation sites has been found for this gene.
There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse LYPLA1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Met1-Asp230 of mouse LYPLA1, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
