Lymphocyte-specific protein 1 is an intracellular F-actin binding protein.
The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration.
Alternative splicing results in multiple transcript variants encoding different isoforms
May et al.
(1993) and others used various cDNA cloning strategies to identify genes preferentially expressed in B lymphocytes.
One gene, variously named LSP1 and pp52, exhibited a number of properties supporting a possible role in B-cell signaling pathways.
The gene codes for a 52kD phosphoprotein expressed only in transformed and untransformed B cells, thymocytes, and untransformed T-cell lines.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry:: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes rat LSP1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to Ser127-Pro331 of rat LSP1, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
