Leukocyte cell-derived chemotaxin-2 is a secreted, 16kD protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts.
This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein.
A polymorphism in this gene may be associated with rheumatoid arthritis.
Neutrophils migrate in response to increasing concentrations of chemotactic factors released from inflammatory sites.
From the culture fluid of a human T-cell leukemia cell line (SKW-3), Yamagoe et al.
(1996) isolated a 16kD secreted protein with neutrophil chemotactic activity and designated it LECT2.
They purified the protein and determined the amino acid sequence.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.5-2ug/ml Immunohistochemistry (Paraffin): 5-20ug/mlImmunocytochemistry: 5-20ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol
Specificity：Recognizes mouse LECT2
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Met1-Leu151 of mouse LECT2, expressed in E. coli.
