84-4425-46　［受注停止］LECT1 (Leukocyte Cell Derived Chemotaxin 1, BRICD3, CHM-I, CHM1, CH-SP, Chondromodulin-1, Chondrosurfactant protein) 200ul　363942

特徴

• LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein.
• The N-terminal of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it.
• The C-terminal of the precursor protein contains a 25kD mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1.
• The mature protein promotes chondrocyte growth and inhibits angiogenesis.
• LECT1 expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion.
• The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- KAQVKAR IPEVGAVTKQ SISSKLEGKI MPVKYEENSL IWVAVDQPVK DNSFLSSKVL ELCGDLPIFW LKPTYPKEIQ RERREVVRKI VPTTTKRPHS GPRSNPGAGR LNNETRPSVQ EDSQAFNPDN PYHQQEGESM TFDPRLDHEG ICCIECRRSY THCQKICEPL GGYYPWPYNY QGCRSACRVI MPCSWWVARI LGMV
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.