CLIM1 and CLIM2 have a very high level of identity to each other and to the homologs in other species.CLIM2 encodes a 375aa protein.human LMO2 interacted with human BEX2.
Electrophoretic mobility shift assays showed that BEX2 and LMO2 were part of a DNA-binding complex that recognized the E-box element.
Other components of this complex included NSCL2 (NHLH2) and LDB1
LDB1 associated with a complex containing LMO4, CTIP, and BRCA1 in transfected human embryonic kidney cells.LDB1 was consistently enriched in the superior temporal gyrus posterior temporal cortex, and perisylvian cortex.
LDB1 may be involved in asymmetric patterning of the developing human cortex.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human LDB1.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Asp112-Gln411 of human LDB1 fused to His-Tag and GST-tag at N-terminal expressed in E. coli.