84-4424-84　KRT33A (Keratin 33A, KRTHA3A, Ha-3I, Krt1-3, K33A, HHA3-I, HKA3A, Keratin,Hair,Acidic 3A, Hard Keratin Type I 3I, Keratin, type I cuticular Ha3-I) 200ul　363881

特徴

• KRT33A is a member of the keratin gene family.
• It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.
• As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails.
• There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B
• Rogers et al.
• (1998) reported that the deduced KRTHA3A protein has 405aa and shares 93.3% aa sequence identity with KRTHA3B.
• By RT-PCR, Rogers et al.
• (1998) showed that KRTHA3A is expressed in the human hair follicle.
• See Langbein et al.
• (1999) for further details on the expression pattern of the KRTHA3A gene in the hair follicle.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.