84-4424-76　KRT18 (Keratin 18, CK18, CYK18, K18, Cytokeratin 18, Cell proliferation-inducing gene 46 protein, Keratin, type I cytoskeletal 18) 200ul　363873

特徴

• Keratin 18 is a type I cytokeratin.
• It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family.
• They are expressed in single layer epithelial tissues of the body.
• Mutations in this gene have been linked to cryptogenic cirrhosis.
• Two transcript variants encoding the same protein have been found for this gene
• Human keratin 18 and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues.
• Endo B and its coexpressed type II keratin, Endo A (the mouse equivalent of human keratin 8), appear to be the first IF proteins expressed during murine development.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- RAQIFANTVD NARIVLQIDN ARLAADDFRV KYETELAMRQ SVESDIHGLR KVIDDTNVTR LQLETEIEAL KEELLFMKKN HEEEVKGLQN QIANSGLTVE LDAPKPQDLS KIMADIRAQY DELAQKNREE LDKYWSQQIE ESTSVVTSQS AEVGAAETT
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.