Kallikrein13 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.
Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer.
An additional transcript variant has been identified, but its full length sequence has not been determined.
in a 300kb region on chromosome 19q13.3-q13.4, where other kallikrein genes are localized.
KLK13 exists in 2 main forms: a long form that encodes a deduced 277aa protein with a predicted molecular mass of 30.6kD, and a short form, referred to as the short KLKL4 variant, that uses an upstream alternative splice donor site located in exon 3 that generates a truncated protein.
The KLK13 protein shares 51% amino acid identity with KLK11 and KLK6.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse KLK13.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Val25-Ala261 of mouse KLK13 fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
