Integrins are cell-surface adhesion receptors that bind to extracellular matrices (ECM) and mediate cell-ECM interactions.
Some integrins are known to play critical roles in dental enamel formation.
ITGB6 expression was strongest in the maturation stage and its localization was associated with ameloblast modulation.Since the protein was clearly distinct from previously described integrins numbered beta-1 through beta-5, they designated the new protein beta-6.
Krissansen et al.
(1992) assigned the gene encoding the beta-6 subunit of integrin to chromosome 2 by analysis of somatic cell hybrids with a fragment of a genomic clone.
They commented on the possible significance of the fact that the gene for vitronectin receptor, alpha subunit (VNRA) also maps to chromosome 2.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human ITGb6.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Tyr131-Leu371 of human ITGb6 fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
