CD61 is a cluster of differentiation found on thrombocytes.
The ITGB3 protein product is the integrin beta chain beta 3.
Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain.
A given chain may combine with multiple partners resulting in different integrins.
Integrin beta 3 is found along with the alpha IIb chain in platelets.
Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling
The platelet and endothelial cell heterodimers use GP IIIa as the beta subunit; the leukocyte heterodimers contain a beta subunit with a molecular mass of 95kD that is homologous to GP IIIa but is clearly a different protein; and the fibronectin receptors contain a beta subunit that appears to be analogous to band 3 of integrin.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse ITGb3.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Asp135-Ile377 of mouse ITGb3 fused to His-Tag and S-tag at N-terminal expressed in E. coli.
