The ITGB2 is a protein belongs to the integrin beta chain family of proteins.
Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain.
This gene encodes the integrin beta chain beta 2.
A given chain may combine with multiple partners resulting in different integrins.
For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1
Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1).
Two transcript variants encoding the same protein have been identified for this gene.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human ITGb2.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Asp451-Ser627of human ITGb2, fused to His-Tag and MBP-tag at N-terminal expressed in E. coli.
