84-4423-76　ITGa1 (Integrin Alpha 1, CD49-A, CD49a, ITG-A1, VLA1, CD49 antigen-like family member A, Laminin and collagen receptor) 200ul　363774

特徴

• CD49a encodes the alpha 1 subunit of integrin receptors.
• This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin.
• The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis.
• The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
• The integrin alpha-1 chain associates with the beta-1 chain (ITGB1) to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells.
• It has a role in cell attachment and neurite outgrowth on laminin and collagen as well as in peripheral nerve regeneration.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-KGGFLACG PLYAYKCGRL HYTTGVCSNV SSTFETVKAV APSVQECKTQ LDIVIVLDGS NSIYPWESVT AFLNSLLRNM DIGPQQTQVG IVQYGQTVVH EFYLNTYSTT EEVMDAALRI RQRGGTQTMT ALGIDTAREE AFTEAHGARR GVQKVMVIVT DGESHDNYRL QEVIDKCEDE NIQRFAIAIL GSYSRGNLST EKFVEEIKSI ASKPTEKHFF NVSDELALVT IVEALGERIF ALEATTDQQA ASFEMEMSQA GFSAHYSQDW
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.