CD49a encodes the alpha 1 subunit of integrin receptors.
This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin.
The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis.
The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
The integrin alpha-1 chain associates with the beta-1 chain (ITGB1) to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells.
It has a role in cell attachment and neurite outgrowth on laminin and collagen as well as in peripheral nerve regeneration.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes rat ITGa1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to Leu119-Leu355 of rat ITGa1 fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
