84-4423-43　INSL5 (Insulin Like Protein 5) 200ul　363741

特徴

• Insulin gene superfamily hormones regulate cell growth, metabolism, and tissue-specific functions.
• Members of this family are characterized by a signal peptide, a B chain, a connecting C chain, and an A chain
• By EST database searching for sequences related to relaxin (RLN1), Conklin et al.
• (1999) identified a cDNA encoding INSL5, also designated ZINS3.
• The deduced 135aa protein, which shares 59% and 40% sequence identity with mouse Insl5 and human RLN1, respectively, has a dibasic cleavage site between the B and C chains.
• Northern blot analysis revealed expression of an approximately 1.0-kb transcript in uterus, rectum, and colon.
• By radiation hybrid analysis and the use of surrounding markers, Conklin et al.
• (1999) mapped the INSL5 gene to chromosome 1p31.1-p22.3.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-RQTVKLCG LDYVRTVIYI CASSRWRRHL EGHFHSQQAE TRNYLQLLDR HEPSKKTLEH SLPKTDLSGQ ELVRDPQAPK EGLWELKKHS VVSRRDLQAL CCREGCSMKE LSTLC
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.