INHBE is a member of the activin beta family that plays a role in pancreatic exocrine cell growth and proliferation.
Hashimoto et al.
cloned INHBE, which they called activin beta-E subunit.
The deduced 350aa protein contains an N-terminal hydrophobic signal peptide and a potential N-glycosylation site.
The proposed cleavage site at aa232-236 would yield a mature 114aa protein.
INHBE shares 97% and 96% similarity with the mouse and rat activin beta-E orthologs, respectively.
The deduced mature human beta-E subunit shares aa identity of 44%, 48%, and 64% with activin beta-A, activin beta-B, and activin beta-C, respectively.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.