84-4423-33　INHA (Inhibin A, INH-A) 200ul　363731

特徴

• Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits.
• Inhibin belongs to the transforming growth factor-beta superfamily.
• In women, FSH stimulates the secretion of inhibin from the granulosa cells of the ovarian follicles in ovary.
• In turn, inhibin suppresses FSH.Inhibin secretion is diminished by GnRH, and enhanced by insulin- like growth factor-1.
• Inhibin A reaches its peak in the midluteal phase
• Inhibin-A is elevated in the blood serum of women carrying fetuses with Down syndrome.
• Inhibin is produced in the gonads, pituitary gland, placenta and other organs.
• In men, it is a hormone that inhibits FSH production.
• The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- ARELVL AKVRALFLDA LGPPAVTREG GDPGVRRLPR RHALGGFTHR GSEPEEEEDV SQAILFPATD ASCEDKSAAR GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP LLGLLALSPG GPVAVPMSLG HAPPHWAVLH LATSALSLLT HPVLVLLLRC PLCTCSARPE ATPFLVAHTR TRPPSGGERA RRSTPLMSWP WSPSALRLLQ RPPEEPAAHA NCHRVALNIS FQELGWERWI VYPPSFIFHY CHGGCGLHIP PNLSLPVPGA PPTPAQPYSL LPGAQPCCAA LPGTMRPLHV RTTSDGGYSF KYETVPNLLT QHC
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.