Ischemia-Modified Albumin (IMA) - In cases of Ischemia - Albumin undergoes a conformational change and loses its ability to bind transitional metals (copper or cobalt).
IMA can be used to assess the proportion of modified albumin in ischemia.
Its use is limited to ruling out ischemia rather than a diagnostic test for the occurrence of ischemia.
Ischemia-modified albumin (IMA) is a sensitive biomarker of cardiac ischemia.
Ischemia-modified albumin (IMA) is a relatively new biomarker in the identification of myocardial ischemia in advance or in the absence of myocardial necrosis.
Since IMA can be detected before troponin and has a high sensitivity (82%) compared to traditional diagnostic tools, it is valuable for the diagnosis of myocardial ischemia in patients presenting with chest pain at the emergency department.
It is well known that IMA rises within minutes from the onset of the ischemic event and remains elevated for several hours after cessation of ischemia.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human IMA.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Native Protein corresponding to human IMA.
