84-4423-29　ILF3 (Interleukin Enhancer Binding Factor 3, DRBF, DRBP76, MMP4, MPHOSPH4, MPP4, NFAT, NF-AT-90, NF90, NFAR1, TCP80, Nuclear Factor Of Activated T-Cells, M-Phase Phosphoprotein 4) 200ul　363727

特徴

• Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2.
• NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2.
• In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase.
• NFAT is a heterodimer of 45kD and 90kD proteins, the larger of which is the product of this gene.
• The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation.
• At least three transcript variants encoding three different isoforms have been found for this gene.
• Viranaicken et al.
• (2006) identified an additional alternatively spliced exon within intron 2 of the mouse and human ILF3 genes, increasing the total number of exons to 22.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- YGSYGYGGN SATAGYSQFY SNGGHSGNAS GGGGGGGGGS SGYGSYYQGD NYNSPVPPKH AGKKQPHGGQ QKPSYGSGYQ SHQGQQQSYN QSPYSNYGPP QGKQKGYNHG QGSYSYSNSY NSPGGGGGSD YNYESKFNYS GSGGRSGGNS YGSGGASYNP GSHGGYGGGS GGGSSYQGKQ GGYSQSNYNS PGSGQNYSGP PSSYQSSQGG YGRNADHSMN Y
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.